Senior Software Developer

at Wellcome Sanger Institute (view profile)
Location Cambridge, United Kingdom
Date Posted April 11, 2019
Category United Kingdom - Tier 1 Visa Jobs
Job Type python


Salary in the region of £41,259 - £49,922 (dependent on experience) plus excellent benefits

The Opportunity

Highly motivated individual required to join team in the design and development of IT Systems & Workflows for Big Data Genome analysis.

An exciting IT opportunity has become available to further develop our IT systems and analysis workflows in the Cancer, Ageing and Somatic Mutation (CASM) Division. The CASM IT team provide support to scientific staff to help in the Group’s aim of increasing our understanding of cancer and ageing.

Specifically, the role will support the design and development of our compute infrastructure to allow our analysis workflows to be run in a distributed, adaptable and scalable environment. This position would be ideal for someone who enjoys working in a team environment to develop IT solutions for large scale data analysis. These solutions need to be efficient, flexible and under continuous integration to ensure reliability. The design and implementation of the user interfaces to these resources used by the scientific staff need to be intuitive and robust. There are many training opportunities to advance technical skills and personal development.

We are looking for an individual who enjoys working in a supportive multi-disciplinary team environment to help solve complex IT issues which will ultimately aid our understanding of cancer and ageing in humans.

The role can be performed flexibly in line with the Wellcome Sanger Institute’s flexible working arrangements.

The CASM Support IT team has successfully developed a suite of algorithms to analyse genetic variation in cancer genome data. This includes software to detect tumour genetic variation (e.g. single-base substitutions, structural rearrangements, copy number changes) and the ability to annotate the resulting variants and mine the data for interesting patterns and signatures (

The CASM Division has led the way in the systematic analysis of cancer genomes by using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers (

Essential Skills

• Good degree in Scientific discipline or Computing 
• Software development skills e.g. Python 
• Keen to learn and share ideas and knowledge 
• Ability to work with scientific staff and translate their requests into reliable and maintainable software 
• Has an eye for detail and takes pride in their work 
• Enjoy working as part of a supportive team 

Ideal Skills

• Ability to work independently, organise own workload and meet deadlines 
• Handling Next Generation sequencing data 
• Experience of using large scale compute farms 
• Developing code in software containers (e.g. Docker) and in cloud environments (e.g. OpenStack) 
• Experience of relational databases 
• Working in an Agile team 

Please include a covering letter and CV with your application. Closing date for applications: 11th April 2019

Visa Assistance

Open to assisting the right candidate with the following Visa(s) / Work Permit(s)

1) United Kingdom - Tier 1 Visa Jobs